|
Gene transfer efficiency of K562-targeted and standard rAAV2 vectors on solid tumour cells. |
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| %GFP+ cells |
MFI (AU) |
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|
|
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| Cell line |
EARVRPP |
rAAV2 |
EARVRPP |
rAAV2 |
|
|
||||
| RM-HS-1 |
46.01 ± 10.82 |
97.61 ± 3.21 |
35.03 ± 12.93 |
395.64 ± 52.93 |
| H-Meso1 |
76.42 ± 2.41 |
88.30 ± 4.34 |
70.29 ± 9.54 |
150.89 ± 23.22 |
| HeLa-RC |
77.94 ± 6.60 |
98.22 ± 1.21 |
32.57 ± 7.73 |
143.49 ± 12.21 |
|
A significant (p < 0.05; irrespective of cell line) superiority of the standard rAAV2 vector on three solid tumour cell lines could be shown for both %GFP+ cells and MFI. MFI: mean fluorescence intensity; AU: Arbitrary units. | ||||
Stiefelhagen et al. Genetic Vaccines and Therapy 2008 6:12 doi:10.1186/1479-0556-6-12 |
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