Figure 1.

Quantitative analysis of vector biodistribution following intravascular administration of AAV8LP-1FIX into rats. DNA was extracted and processed from tissues of rats, which were dissected 4 months after intravenous injections of scAAV8-LP1-hFIX. Purified DNA was subsequently analysed by quantitative real-time PCR using hFIX specific primers designed to hybridise to the human FIX coding region of the AAV8 vector.¹². Data are presented as the means ± standard error of the mean. VG = vector genomes.