Figure 6.

Proliferation of peripheral CD₄⁺ (A) and CD₈⁺ T cells (B) and the expression of Foxp₃⁺ on spleen CD₄⁺ T cells (C) harvested from PBS-vaccinated mice sensitized and challenged with PBS, PBS-vaccinated mice sensitized and challenged with ovalbumon (OVA), pcDNA_3.1-vaccinated mice sensitized and challenged with OVA, OVA- pcDNA_3.1-vaccinated mice sensitized and challenged with OVA, and OVA-Fc-pcDNA_3.1-vaccinated mice sensitized and challenged with OVA. * and ** stand for the p values less than 0.05 and 0.01, respectively, as compared with PBS-vaccinated mice sensitized and challenged with PBS. + and ++ stand for the p values less than 0.05 and 0.01, respectively, as compared with OVA-Fc-pcDNA_3.1-vaccinated mice sensitized and challenged with OVA.