Figure 3.

Neutralizing Titers after single administration of cationic lipid-formulated pDNA in mice. Data points indicate individual animal neutralizing titers 48 Days after vaccination with either 2 μg or 5 μg of cationic lipid-formulated pDNA. GMT values for each group are also indicated (▬). pDNA was formulated with either DMRIE-DOPE (D:D; 4:1 or 2.5:1 molar ratio) or Vaxfectin™ (4:1 molar ratio) as described in Materials and Methods. Protection threshold (0.5 IU/mL) is indicated with a horizontal line.